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Applying the rotarod test, the acute neurological toxicity was determined.
The acute neurological toxicity was determined using the rotarod test.
Cell toxicity was determined with the trypan blue exclusion test.
Toxicity was determined as the level at which plant growth was inhibited.
The acute neurological toxicity was determined applying the minimal motor impairment rotarod test.
Acute oral toxicity was determined by administering these compounds to female Wistar rats in increasing doses (as per the OECD protocol 425).
The lethal dose (LD50) of ABP was found to be 2.25 mg/kg body weight and further the acute toxicity was determined with sublethal doses in normal mice.
Toxicity was determined in human proximal tubule cells by leakage of lactate dehydrogenase or uptake of ethidium homodimer and in erythrocytes by degree of hemolysis.
The effect of Rg1, Rg3 and Rb1 on α-syn aggregation and toxicity was determined by an array of biophysical, biochemical and cell-culture-based techniques.
Using flow cytometry and MTT assay, potential action on cell toxicity was determined for each of the compounds for four cancer cell lines.
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In addition, their oral and parentral acute toxicity were determined.
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