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The present investigation was undertaken to verify whether mitochondria play a significant role in aluminium (Al) toxicity, using the mitochondria isolated from tobacco cells (Nicotiana tabacum, non-chlorophyllic cell line SL) under Al stress.
The capacity of two toxicity bioassays (fertilization and embryo toxicity tests) to discriminate sediment toxicity using the sea urchin Paracentrotus lividus was tested in five stations with different levels of pollution in the Lagoon of Venice.
Then, the cytotoxicity of the most potent compounds (i.e., compounds 6a, 6d, 6e, 6 g, 6j, and 6l) were evaluated for toxicity using the breast cancer cell lines MDA-MB231, MCF-7, and T-47D by using a MTT assay, and no toxicity was observed.
We also include considerations on how to quantify toxicity using the FET results.
Pulskamp et al.[50] failed to observe any acute toxicity using the WST-1 assay in cultured rat NR8383 macrophages and A549 cells on viability and inflammation upon incubation with CNT.
We evaluated acute toxicity using the standard battery of tests recommended by the KFDA.
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At the end of each cycle physical examination, the performance status, and treatment toxicities using the National Cancer Institute of Canada toxicity Criteria were assessed.
Due to more treatment-related toxicities using the 50 mg dose, in most planned trials, a 37.5 mg dose has been used.
Similar toxicities using the combination of panobinostat and MD5-1 were observed in mice bearing a second independently derived Vk*MYC myeloma (data not shown).
So he designed a procedure to screen water samples for environmental toxicity using bioluminescent fungi -- and won the £10,000 prize.
Acute toxicity was assessed using the National Cancer Institute Common Toxicity Criteria (NCI-CTC) scale, version 2.0, combined to Radiation Therapy Oncology Group (RTOG) scale; late toxicity using SOMA-LENT scale.
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