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Cerebral and cardiac toxicity have been observed in some individuals.
Two QSAR models for developmental toxicity have been developed, using different statistical/mathematical methods.
Despite numerous advantages that CNTs present, several cases of in vivo toxicity have been reported.
Symptoms of metal toxicity have been studied in several plant systems and under various conditions.
Hepatoxicity, reproductive disorders and bone marrow toxicity have been related to the occurrence of some chlorophenical (Wageh et al., 2013).
Recently, several dose-finding methods, relaxing the monotonicity assumption of toxicity have been proposed in the literature.
However, multiple cases of renal tubular toxicity have been described in patients with HIV treated with TDF.
Although many studies of lindane toxicity have been carried out, we still know little about the underlying molecular mechanisms.
Compounds with shared basic active structures (BASs) exhibiting G-protein coupled receptor (GPCR) activity and repeated dose toxicity have been mined from small datasets.
Alcohol induced toxicity have been linked with increased oxidation of proteins and lipids to form oxidized proteins and peroxide products, malondialdehyde (MDA) and acetaldehyde (MAA -adducted proteins [22].
Transcriptomic and physiological changes that occur in response to short- and long-term Fe toxicity have been reported (Quinet et al. [2012]).
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