Sentence examples for toxic pathways from inspiring English sources

For the remaining 21 mammalian long-term reproductive toxicants, neither in vitro assays nor structural alerts provide evidence of interferences with EA endocrine receptors and, thus, other toxic pathways are more likely causing the reproductive toxicity.

Since aberrantly localized DPR proteins may invoke different toxic pathways, future studies of cellular and animal models of DPR toxicity will benefit from the careful analysis of the subcellular localization of the aggregates.

Moreover, transcripts related to these toxic pathways were also significantly affected by BT.

Therefore, designing compounds that can inhibit multiple toxic pathways is the most attractive therapeutic strategy in complex disorders like AD.

Further studies are essential to investigate the removal of azole fungicides by advanced treatment technologies, environmental fate such as natural photolysis, and toxic pathways in aquatic organisms.

In view of the proposed mechanisms of PQ toxicity, several therapeutic measures have been taken, at different time points after intoxication, to hamper the toxic pathways [4].

Oxidative stress is thought to be a critical node in the toxic pathway for numerous diseases.

Cells have evolved various organizational systems to solve the challenges of toxic pathway intermediates, competing metabolic reactions, and slow turnover rates.

Segregation of enzymes that catalyze sequential reactions can alleviate challenges such as toxic pathway intermediates, competing metabolic reactions, and slow reaction rates.

The activation of metallothioneins in response to AgNPs and the possibility to reverse the main toxic pathway by Ag+ chelating agents demonstrate a cause/effect relationship between ions and cell death.

Our data illustrate how a seemingly highly toxic pathway can serve for an important physiological function in insects.