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Network-based methods introduce a bias towards terms associated to the most connected nodes (see in our case Figure 1S, Additional file 2).
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The levels of IGFBP2 have been shown to be high in the early to mid-term fetus and then drop markedly towards term.
Developmental changes in AII receptor expression are also seen in the fetus towards term.
PLAP-positive EVs are found circulating throughout pregnancy, with levels increasing towards term.
There seemed to be reporting fatigue in the FM charts, with compliance rates falling towards term.
In contrast to VEGF, the expression of PlGF and the soluble form of VEGFR1 (sFlt1) increase towards term [ 23– 25].
Using flow cytometry, circulating HLA-G-positive EVs were identified throughout pregnancy, with amounts decreasing towards term.
Parallel to its regulation by oxygen, placental VEGF levels are high in the first trimester when oxygen levels are low and decline thereafter towards term of gestation [ 16– 16].
As pregnancy progresses towards term, the myometrium becomes increasingly depolarized, to approximately −45 mV at parturition (Casteels & Kuriyama, 1965; Parkington et al, 1999).
In uncomplicated pregnancies, α-foetoprotein reaches its maximum at the beginning of the third trimester, and drops thereafter towards term (Speroff et al, 1983).
The odds ratios varied widely across gestational age categories, with the association between inadequate/no PNC and both LBW and SGA increasing towards term.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com