Exact(1)
We also performed sensitivity analyses to check the robustness of the rules towards alteration in the parameters.
Similar(59)
This could in turn reflect inherent dosage-sensitivity of vital processes controlled by endogenous TDP-43/TBPH towards alterations in TDP-43/TBPH protein levels and could account for the similar neural impacts separately obtained by TDP-43 overexpression and knock down in vivo [10], [11], [12], [13], [15], [16].
The first genetic link to common forms of migraine was recently reported, pointing the way towards alterations in glutamate homeostasis.
Recent findings point towards alterations in fatty acid oxidation, oxidative phosphorylation and structural proteins in advanced fibrosis.
It is further suggested that human cognitive abilities are very sensitive towards alterations in metabolite levels and even slight brain energy metabolism dysregulations can lead to conditions that are hallmarks of SCZ.
The observed gene expression changes in several genes associated with vesicle fusion and exocytosis including Sv2c (Supplementary Material, Figs S2 and S3) point towards alterations in the secretory pathway in the Mwk cerebellum, which has a known role in dendritic arborization in many neuronal cell types (48).
As a Malaysian, i gladly say that he's vigorous towards the alteration of the American policy in order to regain the global trusts after 8 miserable years of Bush's presidency.
In contrast to enamel, other skeletal tissues such as bone, dentine and cement exhibit much less stability towards diagenetic alteration.
Tooth enamel of large herbivores such as Hipparion (s.l). is considered relatively stable towards diagenetic alteration for millions of years due to their very high degree of mineralization [44], [45].
At the moment, most studies point towards an alteration in synaptic transmission, in a neuromodulatory-type effect [ 7, 8].
However, beside the possibility of a return to normal condition, there is the risk of further evolution towards an alteration that may become apparent at the morphostructural level [ 3].
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