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The nucleotide composition showed heavy biased toward AT accounting to 70.9% of total mitogenome.
Hodgkinia, somewhat mysteriously, shares in this universal bias toward AT mutations.
It has previously been found that bacteria show a mutational bias toward AT [ 52].
11 By contrast, others, such as Plasmodium falciparum, did a compositional transition toward AT.
Stabilizing selection also explains the preference of GC codons in the presence of a high mutational bias toward AT.
Curiously, the two known exceptions are the two genomes that should be most strongly shifting toward AT.
Similar(10)
In contrast, the sequence evolution toward AT-richness was observed in those pericentromeric regions.
In BAC library sequences, SSRs were strongly biased toward AT-rich repeat motifs for both di- and trinucleotide SSRs.
As can be seen from Table 1, the global codon usage in 1180 genes on the chromosome in L. intracellularis shows the expected bias toward AT-rich codons.
From the estimated GCeq values (fig. 4), two different mutational trends are apparent: 1) toward AT-richness in SC regions and 2) toward GC-richness in IR regions.
Comparisons with other Malacostraca show that all nine genomes, like most other mitochondrial genomes, share a bias toward AT-richness and a related bias in codon usage.
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