Sentence examples for tough to effect from inspiring English sources

Hospital region will probably be one of the most challenging determinants, since hospitals cannot move to another geographical region and regional collaborations are embedded, which might be tough to effect change upon.

These diamines were used as co-monomers with PMDA and ODA to synthesize poly amic-acids) which were cast and cured (350°C) to effect imidization, affording tough films.

It was difficult for the bikers to effect a threatening or tough mien on a Buddy, but they tried.

Ecosystems being complicated, it's tough to predict the effects of a shark population collapse.

"It is tough to see the secondary effect yet," Mr. Jackman said.

That may not seem remarkable, but it's tough to overestimate the positive effects of encouragement and acceptance, especially on our most vulnerable populations.

The long term side effects are tough to gauge and an independent study has yet to emerge.

Its network effect may be tough to break.

The question mark on "Flesh Tone" is Kelis's voice, which is so swamped by effects that it's tough to know how engaged she truly is.

The combined effect of all these issues makes it tough to estimate the critical gap.

Tough decision, tough to say.