Sentence examples for totally deficient from inspiring English sources
The phrase "totally deficient" is correct and can be used in written English
It means completely lacking or insufficient in a particular quality or aspect. Example: The student's essay was totally deficient in supporting evidence and failed to address the main argument. In this example, "totally deficient" is used to describe the lack of quality in the essay and emphasizes that it was completely inadequate in meeting the requirements.
"It is a fact that the absence of certain qualities may render the performance of the evangelist's primary function totally deficient," they said.
Adding to the complexity of potential mechanisms is the severe neurodegeneration in mice with mutations in both Siat9 and Galgt, which are totally deficient in the common brain gangliosides (R.L.P., unpublished data).
Strikingly, however, rA75/17red Hko/Hcomp was totally deficient in cell-to-cell transmission, since viral infection remained restricted to the initially infected cells (Fig. 8a d).
Circulating natural IgMs have long been implicated in reperfusion-mediated damage by binding to ischemia-conditioned tissue and activating the complement cascade as shown in mice totally deficient in immunoglobulins [ 45, 46] or complement receptor-2 [ 47].
"Reduced staining" included totally deficient fibers, partially deficient fibers, and fibers with hypodensity of mitochondria; the involved area was semi-quantified as variable focal (<25% of the tissue area), variable regional 25-755% of the tissue area) and widespread (>75% of the tissue area).
For each complex, fibers with strong red (porin) staining but no green staining were considered totally deficient (i.e. homoplasmic for mutant mitochondria), fibers with a patchy green and red staining were considered partially deficient (i.e. heteroplasmic for mutant mitochondria), while fibers lacking both red and green staining were considered mitochondrially hypodense.
We used male immunodeficient nude mice rendered totally insulin deficient by injection of a single high dose of STZ (200 mg/kg).
Expression analyses of MMR and MGMT in MB revealed that all patient specimens (n=74; expression array, n=61; immunostaining, n=13) are most likely MMR proficient, whereas some tumours had low MGMT expression levels (according to expression array) or were totally MGMT deficient (3 out of 13 according to immunohistochemistry).
Diagnostic deficiencies of electron transport chain enzymes were not detected using standard bioassays, but mitochondrial immunofluorescence demonstrated many muscle fibers totally or partially deficient for complexes I, III, IV-I, and IV-IV.
Complex I was the most prominently affected and showed widespread (>75%) reduced expression with many totally or partially deficient fibers, while other complexes showed milder abnormalities; the results are summarized in Table 2.> -wrap-foot> > -wrap-foot> Control values for quadriceps femoris (control values for paraspinal muscle are not available).
Although homogenized paraspinal muscle tissue did not show statistically significant biochemical deficits in electron transport chain activity assays (Table 1), mitochondrial immunofluorescence analysis revealed many totally and partially deficient fibers for complexes I, III, IV-I, and IV-IV (Table 2 and Figure 3).
