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When respective regions of human and hydra XPA were compared, it was found that seven out of the nine important residues are totally conserved in hydra, filled circles), while two are replaced with conservative substitutions, open circles).
If we consider the conservation of the polymorphic nucleotide, 7 of them are totally conserved across species (novel-12, novel-14, novel-15, novel-17, novel-18, rs2075749, rs2075750), 3 present a miss-match in one of the species (novel-13, mouse; novel-40, dog; rs1366610, mouse) and another 3 present two miss-matches (novel-3, cow-dog; novel-42, cow-mouse; rs930102, human-cow).
This peptide contains a core sequence comprised of eight amino acids (GLDFIPGL) that is totally conserved in all leptin proteins studied to date.
A 17-amino acid signal peptide, two thioredoxin domains with two active sites of CGHC, and KDEL retention signal were totally conserved in the deduced amino acid of AjPDI.
Nevertheless neither the clonal nor the cellular organization is totally conserved.
These are totally conserved in the Group 1 and Group 2 alignments.
Similar(9)
For example, it has been reported that treatment with cyclophosphamide negatively affects the number of Treg cells but totally conserves the other Th1 repertory cells [51].
Totally, 284 conserved miRNAs families were found in C. sinensis out of 2,093,879 reads (with 62,512 unique sequences).
Totally, 153 highly conserved pre-miRNAs were identified accordingly.
Among the 55 TUs composing the 38 transcriptons found in both BAp and E. coli, 16 are monocistronic, 13 are identical or similar TUs (totally or partially conserved from gene deletions) and 26 are TUs that were reorganised during genome evolution, i.e., formed from a fusion or split from different ancestral TUs (see Methods section for definition of the different TU rearrangements).
First, with the exception of the fusion peptide, none of the presently identified "conserved" determinants is totally invariant, and each of these relatively invariant determinants may show increased variability under specific immune pressure.
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