Sentence examples for total plasma concentration from inspiring English sources

Protein binding values (fb, fraction bound) are given as the percentage of the total plasma concentration of a drug that is bound to all plasma proteins (Table 1).

Thus, an IQ of 1 or greater means that the achievable total plasma concentration of the drug is equal to or greater than the in vitro 50% effective concentration, and the higher the IQ translates to a greater predicted efficacy.

One indicator of the expected clinical antiviral activity is the inhibitory quotient (IQ), defined herein as the ratio between the average total plasma concentration (Cave) and the 50% effective inhibitory concentration (EC50).

The total plasma concentration of homocysteine is a marker of this amino acid's atherogenic potential.

The pain-relieving effect of amitriptyline appeared to correlate well with the total plasma concentration.

Indeed, the total plasma concentration (free carnitine + acylcarnitine) is only 45 85 μmol/l.

A pharmacokinetic model was developed to assess the disposition of the coencapsulated drugs in mice, including the free and encapsulated fractions after measurement of the total plasma concentrations.

Total plasma concentrations of T3 were inversely correlated with stocking densities, whereas total plasma T4 levels of juvenile barramundi were significantly higher when the juvenile barramundi were stocked at a higher density of 18.75 kg m− 3.

Darunavir (total and unbound) and ritonavir (total) plasma concentrations were measured.

Thirty μL were injected onto the column under the same conditions used for total plasma concentrations.

The total plasma concentrations of AZD3409 ester and AZD3409 acid were determined by LC MS/MS.