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d IgG4 immunostain was positive in up to 50 plasma cells per high-power field, comprising over 50%% of the total plasma cell population (original magnification, ×400).
There were at least 150 180 IgG4-positive plasma cells per high-power field, comprising over 40%% of the total plasma cell population (as assessed by CD138).
However, IgG4 immunostain was markedly positive, with 40 IgG4-positive cells per high-power field (HPF), comprising over 40%% of the total plasma cell population (Fig. 3e, f).
Many of the plasma cells stained positive with IgG4 (Fig. 2g), i.e., about 70 per high-power field, comprising over 50%% of the total plasma cell population.
f Higher magnification reveals >40 IgG4-positive plasma cells per high-power field, comprising about 40%% of the total plasma cell population (original magnification, ×400).
(The total plasma cell population was assessed with CD138 immunostain, and IgG immunostain was also obtained, showing that all IgG-positive cells were also IgG4-positive, i.e., IgG4 IgG ratio of 1, not shown).
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(The total plasma cells were assessed with CD138 immunostain, not shown).
The number of infiltrating T-lymphocytes, macrophages and total plasma cells was significantly higher in AIPC than in CP (3-, 4- and 8-fold increase, respectively).
The numbers of total plasma cells (Vs38c, IRF4) and IgG-expressing plasma cells increased in the red pulp, EFZ and GC of SIV-infected animals, whereas IgA-expressing cells were present in similar proportions in the red pulp of non-infected and SIV-infected animals.
Three patients presented with >10% of total plasma cells in BM aspirates (13%, 14%, and 33%).
The normal subpopulation ranged from 4.4 to 86% (mean 27%) of total plasma cells.
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