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To obtain, for instance, the precision shown in Table 2, accounts for a total of simulations.
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Three independent simulations were carried out for the native and mutant complexes for a total of simulation time.
For each parameter value, the probability of population replacement was determined by the number of successful replacement events occurring in 1000 simulations, for a total of 101,000 simulations per parameter.
The overall N > S normalization was adjusted to yield a few hundred detectable sources per simulation, a compromise aimed at reducing source confusion while limiting the total number of simulations required to obtain good statistics for the characterization.
Out of 10 000 events, 2485 of the simulated flows crossed the perimeter of the site, or 24.9%percentt of the total number of simulations.
After simulating several thousands of independent simulation runs of this process, a fixation probability of the mutant is estimated as the number of independent simulations in which fixation occurred over the total number of simulations.
The total number of simulations is stopped at 500 at each location; running simulations beyond this number did not result in a significant increase in the variance of possible outcomes of coral cover change.
a The approximate likelihood is shown, calculated out of total number of simulations for each scenario.
The probability of success is the fraction of successful patient profiles out of the total number of simulations.
The SE was also averaged over the total number of simulations.
The models presented here represent a very small sample of the total number of simulations run during the development and testing of the model.
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