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After setting a minimum module size of 30 and merging modules with highly correlated (r > 0.85) eigengenes (defined as the first principal component of a given module and may be considered as a representative of the gene expression profiles in that module), a total of 30 modules were found (excluding the grey module, which is used to hold all genes that do not clearly belong to any other module).
Using the time-based approach, we selected 50 functional modules from each stage, which resulted in a total of 192 modules that we inserted into our observed module set after removing duplicate modules.
Thirdly, a WGCNA approach was used to discover possible modules consisting of groups of genes with similar transcript abundance, either across time or between genotypes of both, and 27 modules out of a total of 47 modules showed significant variation in transcript abundance across time points or genotypes or their combinations (Additional file 8: Table S5; Additional file 9: Figure S4A-C).
In the first design of the TE cooler, the optimization goal is geared towards determining the optimum ratio of the number of TE modules between stages when the total number of modules is kept constant, while in the second design configuration, it is to solve for the optimum ratio of electric current between stages.
Defining the total number of modules for utilization of the design discharge should be a compromise between enabling a flexible operation and limiting the system's complexity.
It can be seen that the total number of modules and the initial SOC of the OBESS for both Case 1 and Case 2 are 11 modules and 44.8%, respectively, whereas 10 modules and 40.9% of the initial SOC of the OBESS for Case 3 obtains the best fitness function.
Then, for a given test order t and a set of d dependencies to be broken, the attribute complexity A is calculated according to Equation 1, where n is the total number of modules and k is any module included before the module i, in test order t.
The total number of modules in the different categories of Table 2 exceeds the number of sequences (222) owing to the multi-modular nature of the dockerin-containing proteins.
Figure 2 shows the total number of modules of each group's mean network over the entire range of sparsity.
Additionally, the time complexity of these algorithms is quadratic to both the number of miRNA and mRNA multiplied by the total number of modules per iteration.
The total numbers of modules, distinct subgraphs, and distinct subgraph patterns for each cancer PPI network are shown in Table 1.
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