Sentence examples for total mediator from inspiring English sources
But the minimum (sufficient) number of binding events that must occur in order to effect mediator release or total mediator release is unknown.
It is noteworthy that in our study, the SOC scale score functioned as a total mediator of HRQoL ratings between the pre-diagnosis phase and 6 months later in three dimensions: overall quality of life and cognitive and social functioning.
As shown in Figure 2B, pooled serum from patients 3 6 released approximately 10% of the total mediator content measured as β-hexosaminidase (a surrogate marker for histamine), which was significantly greater than spontaneous release or a negative control.
As a rule of thumb [ 42], when the results of the first and second steps of MLR analyses are significant, the degree of SOC is a total mediator if the correlation between the independent (T1 scale scores) and dependent variables (T2 scale scores) is non-significant in the third step.
Satisfaction with self and family were the predominant mediators of mental health and global QOL (45% total mediation), and of physical health and global QOL (68% total mediation).
The direct effect of treatment on change in ESS total scores (mediator) was estimated by ANCOVA, which included terms for baseline, center, and treatment.
A total of 165,523 Mediator model configurations were produced.
We discuss the role of the SOC as a total or partial mediator between ratings of HRQoL dimensions at baseline (pre-diagnosis phase) and 6 months later.
In total, 21 inflammatory mediators were thus assessed over time in the following experimental scenarios: no treatment (n = 6 mice per group); 1, 2, 3, or 4 h following surgical cannulation trauma (ST; n = 6 mice per group); or 1, 2, 3, or 4 h of ST + HS (bleeding to 25 mmHg; n = 6 mice per group).
In total, 11 soluble mediators were measured in the synovial fluid of healthy donors, donors with symptomatic cartilage defects and osteoarthritic donors.
Of a total of 23 mediators targeted, 14 could be reliably identified and quantified in SF samples based on detection of characteristic fragment ions at retention times similar to those of commercial standards.
