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After InI (T0), 57 participants (39%) had terminated the programme and a further 30 (20.5%) participants were lost for the T2 measurements, for a total dropout of 87 participants (59.5%).
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To reach a sample size of 128 patients under consideration of a total dropout rate of 30%%, a total of 180 patient-relative tandems shall be randomised.
On the basis of such considerations, a total sample of 92 participants (n = 23 for each condition) is required taking into account a total dropout rate of 20% to detect this large difference with an alpha of 0.05 two-sided and a power of 0.82.
The total dropout rate was 8% of the participants (3% in the control group and 5% in the intervention group).
Maximum total dropout /lost to follow-up rate is estimated at 15% with the majority of dropouts occurring in the first six months of follow-up.
States differentials vary more in total dropout rate.
In table 4, the disorders of the subjects are indicated, and also the percentages of total dropouts and integrations.
Function at post-treatment and the number of total dropouts were adopted as secondary endpoints.
Taking into account a dropout of 25%, in total 176 patients will be included.
Considering an estimated 10% dropout of enrolled subjects, a total of 66 subjects were planned.
Taking into account a dropout of 10%, this results in a total of n = 199 participants.
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CEO of Professional Science Editing for Scientists @ prosciediting.com