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Covariate: total cognition (derived from processing speed, social information processing and cognitive control) b SSRS Social Skills Rating System, total score (self-control + assertion + cooperation + responsibility).
It also accounted for the fact that we have multiple cognitive tests per assessment, as it effectively treats each cognitive test score as a repeat measure of underlying total cognition.
This section describes the results of two groups of estimations: (i) models where the dependent variable is the total cognition score (Table 3) and (ii) models for each component of cognition (Table 4).
Covariate: total cognition f Peer problems score from Strengths and Difficulties Questionnaire.
Covariate: total cognition c Hyperactivity-inattention score from Strengths and Difficulties Questionnaire.
After covarying for total cognition, the group difference regarding autistic traits reduced but remained significant.
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The pre-specified co-primary efficacy measures from the original study were change from baseline in SIB total score (cognition) and the CIBIC-plus global change scores at week 24.
Coprimary efficacy measures were change from baseline in SIB total score (cognition) and the Clinician's Interview-Based Impression of Change-plus caregiver input (CIBIC-plus; global function) score at week 24.
The current sample provided internal reliabilities of 0.90 (total need for cognition), 0.81 (need for cognition: ability), 0.82 (need for cognition: favourability), 0.79 (total faith in intuition), 0.74 (faith in intuition: ability), 0.63 (faith in intuition: favourability).
Non-differential misclassification of cognitive status is likely, but is mitigated by the use of all available cognitive data to consider the association between BC and total metrics of cognition.
The total score for cognition can range from 0 to 14 points.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com