In order to reject contributions from venous vessels when evaluating total arterial blood flow in the central retinal arteries (cp. Section 3.2), flow oriented away from the pupil was excluded from the integration.
In this previous work, PC-MRI revealed that normal ageing is associated with a significant reduction of total arterial blood flow and of the systolic peak sharpness, with a related reduction in venous flow.
These fragments of clot may be small, causing no detectable manifestations, or large, causing obstruction of either the total pulmonary arterial flow or of flow to an area of lung.
Our preliminary data show that a-MCI patients present with high systolic arterial peak flows, which are associated with higher mean total cerebral arterial flows.
Flows in the ICA and VA on the left and right sides were summed to generate the total arterial cerebral blood flow (tCBF).
Statistically significant higher values in the total 60-minute arterial flow were found at t2 and t3, while at t1 only a trend towards increased flow in the intensively treated group was indicated.
The difference in total arterial and total venous flows over a CC corresponds to the arteriovenous (AV) curve, which is shown in Figure 2.
Krejci and colleagues now report, in this issue of Critical Care, that infusing 'low-dose' AVP during early, short-term, normotensive and normodynamic fecal peritonitis-induced porcine septicemia markedly reduced both renal and portal blood flow, and consequently total hepatic blood flow, whereas hepatic arterial flow was not affected.
See related research by Krejci et al., In this issue of Critical Care, Krejci and colleagues report that infusing 0.06 IU kg-1 h-1 arginine vasopressin (AVP) during porcine fecal peritonitis reduced renal, portal and, consequently, total hepatic blood flow, whereas hepatic arterial flow was not affected [ 1].
