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The test, invented in 2005 and nicknamed the "BED test," for the B, D and E viral subtypes it uses, measures H.I.V. antibodies in the blood relative to total antibodies.
The concentration of total antibodies in nestling plasma decreased in parallel with maternal DNP-KLH specific antibodies and was, therefore, assumed to be maternal in origin.
Polyclonal B cell stimulation through parasite mitogens coupled with the secretion of parasite specific antibodies can explain the higher amount of total antibodies observed in infected compared to control groups [25], [26], [28].
Western blot analysis was performed with phospho- and total antibodies.
The detection of total antibodies to melioidosis by IFAT was performed as previously described [ 13].
In healthy animals, the evolution of PCV2-neutralizing antibodies coincided with that of total antibodies.
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The Lyme Multiplex assay detects total antibody levels.
Thus, the results indicated a low (0.06%) total antibody prevalence to hantaviruses in Spain.
Conclusion: The HHV-6 IgM ELISA seems valid to diagnose primary HHV-6 infection in particular in combination with the HHV-6 total antibody assay.
These results support the notion that the magnitude of the total antibody response cannot be used as a measure of protective immunity.
Fig. 3 Concentration of total antibody and gp140 specific antibody.
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