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This represents the highest purified total and functional yields for A2aR yet achieved from any heterologous expression system.
Dosimetric parameters, including dose to 95% of the planning target volume (PTV D95%), percentages of total and functional liver volumes, which received doses from 5 to 30 Gy (V5 to V30 and fV5 to fV30), and mean doses to total and functional liver (MLD and fMLD, respectively) of the 2 plans were compared.
For analysis of total and functional tumor vasculature, t-tests were performed to determine significant differences between groups.
We observed different effects of chemotherapy on total and functional vasculature, thus emphasizing the importance of analyzing changes in functional vasculature.
For both experiments, exogenous surfactant administration led to increased total and functional surfactant in the treated groups compared to the controls.
The total and functional repertoire of TRBV genes in the human TRB locus and in the third assembly of the bovine genome as well as the bovine TRBV gene repertoire identified from cDNA analysis.
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Blood samples were analyzed for MP (absolute total values) and functional markers (percentage values) by flow cytometry.
Orthotopic MCF-7 xenografts treated with 5-FU had a significantly lower number of total (CD31+) and functional (DiOC7+) blood vessels, and a lower percentage of functional vessels on Day 12 after treatment.
There was a significant decrease in the total (CD31+) and functional (DiOC7+) blood vessels on days 4 and 12, and on days 4, 8, and 12, respectively, following a single dose of paclitaxel (P < 0.05).
Interestingly, there was a significantly lower number of total (CD31+) and functional (DiOC7+) blood vessels, as well as a lower percentage of functional vasculature, in orthotopic MCF-7 tumors taken on Day 12 following 5-FU treatment as compared to ectopic (subcutaneous) MCF-7 xenografts.
Total testicular, TART, and functional (total testicular−TART) volumes were estimated using the formula for a prolate ellipsoid (maximal length×maximal width×maximal depth×0.523) (16).
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