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The VSNR was obtained dividing the total amount of signal by the total amount of noise.
This approach registers all gray matter (GM) and white matter (WM) images to an averaged-size template created from all subjects used in this study and modulates the images to preserve the total amount of signal from each region in the images.
After the PVE correction, the DARTEL flow fields calculated from the MR images were applied to their respective PET images to obtain an anatomically exact overlap between GM and PET images of all subjects with modulation to preserve the total amount of signal from each region.
The percentage of glycosylation for every time point was determined by dividing the signal of the glycosylated species by the total amount of signal (0-Gly + 1-Gly).
A convenient way to parameterize signals of differing duration, while keeping the total amount of signal ∫ f(t) dt = α fixed, is to consider the function, (15) f (t ) = α t e − t / τ d Θ (t ) ∫ t e − t / τ d Θ (t ) d t, where Θ t) is a Heaviside step function, τd sets the signal duration, and α is taken to be 1 (α = 1) in the appropriate units.
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There was a high variation between males with respect to the total amount of signaling (Fig. 1C, D).
The resulting ratios for all the probe locations on each chromosome were normalized to the total amount of signals in each fluorescent channel and smoothed with a 6 kb window using a Lowess smoothing algorithm as previously described (Feng et al. 2009).
The percentage on the right indicates total amount of SUMO signal remained after 2 hr.
Loading differences were accounted for by measuring the total amount of TAMRA signal per lane.
Thus, we calculated the HER-2 signal based on double normalization with total amount of protein and the GAPDH signal.
SFR measurements of the 561 combinations of optical properties were each simulated for 7 different fiber diameters (d fiber ∈ [0.2,0.3,0.4,0.6,0.8,1.0,1.5] mm) leading to a total amount of 3927 simulated SFR signals.
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