Although topical – released just after John Lennon's murder – it was not a hit.
The effect of alternate layer arrangements on the drug-release profiles was also investigated to plan for controlled topical drug release from fibrous scaffolds.
"There's a real validity to topical time-release products," said Dr. David E. Bank, assistant clinical professor of dermatology at Columbia-Presbyterian Medical Center, who said he believed they are the logical sequel to time-release oral medications.
A1 Nominee's Records Released As a young lawyer in the Justice Department at the beginning of Ronald Reagan's presidency, John G. Roberts advocated judicial restraint on the issues of the day, many of which are still topical, documents released by the National Archives show.
Earlier evidence found that topical PG analogs release endogenous prostaglandins.
There is an interest for designing topical formulations that release NO/NO donors directly at the desired application site.
This study focuses on the encapsulation of citric acid which has anti-fungal properties into a Mg-Al layered double hydroxide (LDH) in order to be used as slow release topical skin formulations.
The difficulty in developing a topical, long-term release system is a probable reason that more attention has recently been given to the delivery of drugs from other administration sites in the eye.
This approach comprises the use of a cell-free instructive scaffold that incorporates and releases topical chemotactic factors to recruit host endogenous stem/progenitor cells for tissue regrowth at the locus of implantation.
These could be very useful in topical applications where one release will happen at body temperature, followed by another stimulus-triggered release intracellularly or at an inflammatory site.
