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Updated at 3.37pm BST 11.30am BST Some more topical evidence on this subject.
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On the basis of current published evidence, topical capsaicin 8%, smoked cannabis and Nerve Growth Factor have evidence of efficacy in pain associated with HIV-SN.
The second review assessing the effects of interventions for skin damage in leprosy [13] found weak evidence favouring topical ketanserin over clioquinol cream or zinc paste [14] and topical phenytoin over saline dressing [15], [16] in ulcer healing.
BMS treatment remains controversial [25] yet there is little evidence that topical clonazepam helps [16].
In addition, there is limited evidence that topical steroids improve the sense of smell, especially in patients with seasonal AR.
While the 'quality' discourse and the 'e-learning' discourse are topical, there is little evidence of research projects which attempt to diminish the gap between them (Reid, 2003).
In the present study we provide evidence that topical administration of 6, 8-dithiouric acid accelerates wound healing in mice by a mechanism that may involve actions of the UA analog on fibroblasts, keratinocytes and vascular endothelial cells.
There is evidence that topical COX2 inhibition is effective in capsaicin pain model in humans [ 24].
Here, we present evidence that topical administration of imiquimod has a beneficial effect in the management of CBM.
There is no evidence that topical capsaicin works through a transdermal systemic delivery into tissues other than the skin.
The role of statins in AMD is clearly topical and the current evidence is contradictory (see also Table 5).
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