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Over the last decades, there is an ongoing trend to use Intra-articular injections of either corticosteroids, analgesics/anti-inflammatory drugs, polymerized collagen, anti-cytokine drugs, or hyaluronic acid as alternative modalities to maximize the topical effect and minimize the systemic adverse effects [17].
There is little information on the concentration of tranexamic acid needed for topical effect.
This finding suggests that the topical effect of GSSG on the inflammatory response occurs via UV-induced oxidative stress.
We had also speculated that high concentrations of n−3 PUFAs might have a topical effect on gut mucosae.
At some sites, cottonoids or pledgets were also used, soaked with pontocaine or cocaine, and inserted into the middle meatus for additional topical effect.
Sucralfate, which does not alter gastric pH, exerts its topical effect on ulcer disease by binding to the proteins of the ulcer site.
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These data provide new rational for designing more effective and safe antineoplastic PPARγ ligands with topical effects.
To confirm the impaired effect of the SNS innervation and activation on the corneal wound healing described above, we tested the topical effects of isoproterenol (ISO), an isopropyl analog of epinephrine, as a nonselective βAR agonist to locally reconstitute epinephrine in both the 6-OHDA-treated and the balanced salt solution (BSS -sham control groups.
To confirm whether neutrophil recruitment to the wounded cornea is mediated by the release of epinephrine and norepinephrine from the SNS, we checked the topical effects of ISO as a nonselective βAR agonist in locally reconstituting epinephrine in both the 6-OHDA-treated and PBS-sham control groups.
By 2000, however, the topical effects of fluoride (in both water and toothpaste) were better understood.
In typical guy fashion, I may have made a beeline for the inner thighs a bit too early, but the topical effects began to kick in after a few minutes, and she got a slight body high going. .
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CEO of Professional Science Editing for Scientists @ prosciediting.com