The key factors in the management of anti-inflammatory topical diseases are not only related to the use of effective topical anti-inflammatory agents but also in providing skin hydration and barrier repair [ 1].
Systemic and topical fungal diseases are serious human infections especially in immunocompromised and cancer patients.
Since the majority of psoriasis patients have mild or moderate disease, topical corticosteroids, which reduce inflammation and decrease the rate of skin cell growth, are the most commonly prescribed topical treatment for psoriasis [ 45].
Its evolution can be traced back to ancient Egypt (c. 2600 BC) when philosophers serving as clinicians, observed and promoted the use of various dietary and topical remedies for disease (e.g. fruits, linseed oil).
In mild disease, topical treatments and lifestyle modification may be adequate.
Because chancroid is a genital ulcer disease, topical administration appears to be the most likely choice.
If the associated skin psoriasis is not systemically treated, or if nail psoriasis is the sole manifestation of the disease, topical therapies are the appropriate first choice.
Treatment of corneal disease includes topical antibiotics and topical cycloplegic (short term), and corneal patching for 24 h is indicated if the original insult is of nonorganic nature (not from plant or soil sources), for large corneal lesions (>2 cm), and in non contact lens users.
Results demonstrated that lipid nanocarriers constitute a suitable approach for application of methotrexate in skin-related diseases topical therapy.
