Sentence examples for topic of substantial from inspiring English sources

Tear proteomics in keratoconus has been a topic of substantial discussion and speculation over many years.

The use of the DMT in real clinical practice setting has been a topic of substantial debate for payers at hospital and CCAA level.

Calculating relative free energies is a topic of substantial interest and has many applications including solvation and binding free energies, which are used in computational drug discovery.

Although Mental Health Literacy (MHL) has been a topic of substantial interest, measurement of this concept using a scale-based measure has been limited, including a lack of psychometric and methodologically robust scale-based measures of MHL.

Health workers' motivation has emerged as a topic of substantial interest in this context.

The definition of a successful IS has become a topic of substantial research and debate [ 3- 7].

But Dr. Lisa Capaldini, a San Francisco primary care physician, says that anal Pap tests had nonetheless emerged in the past couple of years as a substantial topic of debate among her colleagues.

Another substantial topic of the book is just how incorrect most of the information collected about us actually is.

The sensational nature of early transfusions made them a frequent topic of write-ups, now a substantial historical record.

The topic of singular boundary value problems has been of substantial and rapidly growing interest for many scientists and engineers.

Even on the topic of weight control, where some found substantial differences [ 39], we found no indication that more women than men consider this an important con of quitting.