To simplify analysis, we assign each crime event to its dominant topic, defined as the topic which shares the greatest overlap in words with the narrative text for the crime.
For analysis on the transcriptional level topic defined microarray experiments were employed.
In this study we used a topic defined mRNA microarray for toxicology relevant genes, provided by Miltenyi as the PIQOR platform.
Two-dimensional difference gel electrophoresis (2D-DIGE) based proteomics and topic defined gene expression microarray-based transcriptomics techniques were used to evaluate stress responses in human omental peritoneal mesothelial cells in response to heat- or filter-sterilized PD fluids.
The starting point for such studies is that discourse guides certain ways of talking about a topic, defining 'acceptable' ways to talk, write or conduct oneself and that this can serve a range of social functions.
For investigating potentially involved regulatory mechanisms both protein and RNA levels of HPMC undergoing treatment with H-PDF or F-PDF for 24 h were analyzed by 2D-DIGE and topic defined gene expression microarrays.
0.8 μg of total RNA was then used for amplification and analysis with topic defined PIQOR Toxicology Human Microarray (Miltenyi Biotec, Bergisch Gladbach, Germany) containing 1264 human genes comprising the subject areas apoptosis, DNA damage and repair, inflammation, cell proliferation and response to oxidative stress, and xenobiotic metabolism.
In this study we have used two-dimensional difference gel electrophoresis (2D-DIGE) based proteomics and topic defined gene expression microarray-based transcriptomics techniques to evaluate mesothelial stress responses in response to exposure to heat- versus filter-sterilized PDF, thus comparing effects of GDPs on a global level.
The program is highly structured, based on a manual for counselors, with topics defined for each therapy session and homework assignments for participants.
Since the leading cause of death are cardiac diseases, engineered heart tissue (EHT) is one of the most appealing topics defined in tissue engineering and regenerative medicine fields.
