(C ) Left, average slope (top) and variance of the slope (bottom) of the same individual ABGCs as above with various ages (gray crosses).
In a similar manner, we applied the CA to metabolite profiles with the highest variance (top 10%, top 50% and all) to obtain the principal factors which contain most information.
The heat map in Figure 2 shows the detected miRNAs displaying highest variance (top 30th percentile) throughout differentiation.
Differential analysis was performed with the SAM method (MeV, version 4.8.1) after application of a variance (top 20% of transcripts were kept).
In Figure 9, top left, the variance is zero for all s 1 f and s 1 m, because s2 = 0 (Equation 54).
Similarly, in the other study [ 64], liver tissues as well as omental adipose, subcutaneous adipose, and stomach tissues were collected from 1,008 patients during RYGB (Roux-en-Y gastric bypass); 651 liver samples were gene expression profiled and genotyped, and 7,593 genes with top gene expression variance were selected for Bayesian network reconstruction.
For testing cluster robustness, we used a re-sampling approach in which we randomly excluded five samples from the dataset, then selected the top 40% highest variance genes and performed clustering using the partitioning around medoids (PAM) algorithm with k = 5.
The genes whose variances of the log ratio across all experiments were among the top 1 percentile of variance of all genes were identified as discordant due to hybridization bias.
However, on top of the genetic variance in litter size, there is considerable residual variation between sows for litter size (total number born).
The top frames display the variance coefficient reduction (R σ ) for the total standard deviation σ.
