Sentence examples for top template from inspiring English sources
The F1 target sequence was inserted at two different positions with respect to the promoter: +28 (top template) and +181 (bottom template).
If DCDs are detected in the threading alignments, segments from separated sequences will be merged into single domains under the guide of the top template domain clusters and the target-template alignments.
Both LoopIng and other template-based methods (i.e. FREAD, LoopWeaver) use the stem distance as a filtering step to select the top template loop(s) from a database of known structures.
LOMETS identified the top template from 2 × 0cA, which has the same architecture to the target but with domains containing swapped segments (Szilagyi et al., 2012) (Supplementary Fig. S1B); this results in an incorrect split (1 98) (99–162) (163–241) (242–311) by ThreaDom (Supplementary Fig. S1C).
Fasten the microwave to the base of the cabinet above using screws where directed on the top template.
If your microwave came with a top template, tape it to the base of the cabinet above and drill 3/8"(10mm) holes through attachment points where directed to fasten the microwave to the cabinet base.
That is, for a given target, HHpred first searches through all templates using local alignment, and then realigns the target to its top templates using global alignment.
That is, HHpred first searches through the template database using local alignment and then re-aligns a target to the top templates using global alignment.
As most of the top templates by LOMETS have discontinuous domain structure, ThreaDom classified the target as a discontinuous domain protein.
For example, Zhang-Server (Zhang, 2009) first does a consensus analysis of the results generated by ∼10 individual threading programs and then refines models using distance restraints extracted from top templates.
Then alignments between the target and one or more of the top templates in each of the ranked lists are greedily combined into a multiple sequence alignment (Cheng, 2008).
