More importantly, this and another SOX6 SNP, rs4756846, ranked at top in significance (top 2 for bivariate association with BMI-hip BMD and top 5 for association with FM-hip BMD) among the ∼380,000 SNPs tested genome-wide (see Appendix S2).
These two SOX6 SNPs ranked at the top in significance for bivariate association with BMI-hip BMD in the male subjects among all the ∼380,000 SNPs examined genome-wide.
The two SNPs ranked at the top in significance for bivariate association with BMI and hip BMD in the male subjects among all the ∼380,000 SNPs examined genome-wide.
For comparison of the results between the dual-modality microendoscope and the bench-top microscope, significance was determined by a Student's 2-sample t test, p < 0.05 (OriginPro 8, OriginLab).
Values on the top left are significance levels for the differences in mean N max 2 by the moving block bootstrap method with block sizes of (from top to bottom) 10×10×5, 20×20×10, and 40×40×10 grid points (or, equivalently 200 km × 200 km × 5 h, 400 km × 400 km × 10 h, and 800 km × 800 km × 10 h) in the x, y, and t directions.
Back then I was more of a looker and less of a seer, so the climax of reaching the top held less significance for me than it would have today.
Since 1998, this species has also been observed in the USA and given a top national quarantine significance (Cowie et al. 2009) and is suggested to further expand with climate change (Knop and Reusser 2012).
Using conditional analysis, we determined a set of correlated SNPs and small indels whose effects were statistically indistinguishable from rs214782 (Top) at a significance cut-off of P = 10−4 (see Materials and methods).
Behavioral salience is proposed to arise from bottom-up processes such as the sudden appearance of a novel object [80], [81] and by any internal analysis of an object related to reward, arousal, choice, social significance (top-down)—in short anything that an animal might find significant either by natural inclination or by training [79].
