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To demonstrate the predictive potential of our top prediction, we implemented computational models to distinguish MI from control samples using this gene's expression data.
Fig. 4 Evolution during the training loop of prediction error (top), prediction uncertainty (middle) and fraction of predicted chemical shifts (bottom) for the test molecules.
Axon guidance was among the most significant pathways to be affected by the predicted target genes and was the top prediction for miR-9, miR-30 and miR-20.
Unfortunately, there was no agreement between the results of the three disulphide bond predictors: each top prediction contained a different set of three predicted disulphide bonds.
Of five exons we tested (the five exons are on the top prediction list), four have apparent PCR products excluding the predicted conditional exons (Fig. 5B), while the fifth does not yield any PCR product maybe due to low expression level.
One boy called out: "A hermit?" After explaining abstinence, Mr. Myers asked if anyone wanted condoms, which produced an eager show of hands from the boys and blustery predictions about how many they would use over the course of the weekend (100 was the top prediction).
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The predictive models and the genome-wide top predictions are freely available to scientific researchers.
Amongst the top predictions for COX is a known antiinflammatory drug Cicloprofen (D03489), so the high predicted score is encouraging.
A major challenge in computational protein design is to identify functional sequences as top predictions.
For every WADA class, a heat map with the top predictions (PR-score ≤ 0.05) was calculated.
Fig. 3 The Success Rate (SR) as a function of the number of the top predictions (N) for HawkRank, ZRANK, dDFIRE and FireDock.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com