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The one hundred probes with the greatest differential intensity (p < 0.004, jointly) were determined by selecting the top median log ratios from eight-paired microarrays.
The odds ratio for incident type 2 diabetes in the top (median 25-OHD, 33.4 ng/ml) versus the bottom (median 25-OHD, 14.4 ng/ml) quartile was 0.52 (95% CI 0.33 0.83).
IC50 determination was done using the Prism 5.02 software with constrain of the bottom (median of basal sprouting) to 0 and top (median sprouting induced by the respective growth factor) to 100% using non-linear regression (four parameter fit).
If this method works, a simple functional categorization of genes in the top, median and bottom-ranked genes should roughly show the following pattern: dominance of genes involved in the highly conserved translational process in the bottom-ranked genes, and dominance of genes involved in metabolism in the top-ranked genes.
Caffeine intake was not associated with breast cancer-specific (HR for top (median intake 488 mg per day) to bottom (median intake 155 mg per day) quartile=0.99; 95% CI=0.74 1.33; ptrend=0.93) or overall mortality (HR for top to bottom quartile=1.07; 95% CI=0.88 1.30; ptrend=0.67).
Similar(55)
But according to Fortune, which put a pinstripe-clothed pig on its cover, median pay among top executives rose another 14percentt.
The ratio of top to median pay may, as bosses insist, be irrelevant to sound management.
The report, which is being considered at the highest levels of government, said remuneration "must be brought back into the context of the pay of the rest of the workforce through the disclosure of the ratio of top to median pay".
Crosses indicate means, while boxes indicate 75th percentile (top line), median (middle line), 25th percentile (bottom line) and error bars indicate extreme values of data range.
Then, considering the proteins that did not appear in more than 5 cell lines, Top.CL was defined as the proteins in the top 25% median emPAI (463 proteins).
It topped the median forecast of 68 points among economists polled by Reuters and beat December's preliminary figure of 67.7.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com