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The new studies take steps in a different direction, using the latest genetic and other tools to activate specific memories on command.
Here, TLR agonists in glioma immunotherapies have also been promising as tools to activate APCs and effector T cells, and in general to reverse glioma induced suppression of maturation of these cell types.
As activists, we have tools to activate.
In this current study, we have used IFN-γ along with the TLR4 agonist LPS as classical tools to activate Mo to M1 polarization and induce cytokine production.
Here, we present transcription activator-like effector (TALE) proteins as potent tools to activate HIV-1 specifically.
Here we demonstrate the technique and the feasibility of using novel adeno-associated viral (AAV) tools to activate (AAV-CaMKllα-ChR2-eYFP) or silence (AAV-CaMKllα-eNpHR3.0-eYFP) neural activity of rat prefrontal cortical prelimbic (PL) pyramidal neurons in vivo.
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It may be a useful tool to activate enhance from specific promoters or in activation tagging.
In a control experiment, GAT was coprecipitated from HeLa cells expressing Arf1 alone, but when Arf1 was coexpressed with host ARNO, an Arf GEF used as a tool to activate Arf1, coprecipitation of GAT was increased, confirming Arf1 activation.
Mesenchymal stem cells (MSC) as vehicles of therapeutic genes represent a unique tool to activate drugs within a neoplastic mass due to their property to home and engraft into tumours.
Using the well-defined matrix as a tool to activate integrins α5β1 plus αvβ5, α6β1 and α9β1, individually and in combination, differential integrin activation was demonstrated to exert exquisite control over ESC fate decisions.
Thus, such treatment can be employed as a tool to activate the cytokinesis checkpoint [2], [3], [10].
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