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MADS: a tool for discovery of differential alternative splicing by exon array.
To further demonstrate the application of this screening tool for discovery of new anti-diabetic drugs, we screened >200 new candidates selected from Chinese medicine and identified 49 compounds from different classes which reduced TG content by >50% at 1 μM or >75% at 10 μM.
Here we describe a human epigenome peptide microarray platform as a high-throughput tool for discovery of the factors that sense chromatin modifications.
MarkerMiner is an easy-to-use and effective tool for discovery of putative SCN loci.
Our study demonstrates that microarray-derived gene expression data can provide a tool for discovery of candidate biomarkers for SSAKI.
Primary human tissues are an invaluable widely used tool for discovery of gene expression patterns which characterize disease states.
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Biological libraries are powerful tools for discovery of new ligands as well as for identification of cellular interaction partners.
Altincicek, B. et al. Tools for discovery of inhibitors of the 1-deoxy-D-xylulose 5-phosphate (DXP) synthase and DXP reductoisomerase: an approach with enzymes from the pathogenic bacterium Pseudomonas aeruginosa.
New high-throughput sequencing technologies could provide powerful tools for discovery of novel r5′UTRs, but the size and complexity of the datasets generated by these technologies makes it difficult to differentiate r5′UTRs from the multitude of other types of RNAs detected.
Sequencing and analysis of ESTs is one of primary tools for discovery of novel genes, especially in non-model plants.
Altogether, these data illustrate the therapeutic utility of the cancer stem cell concept, which provides the tools for discovery of novel mechanisms of cancer therapeutic resistance.
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CEO of Professional Science Editing for Scientists @ prosciediting.com