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Other conservation laws, in particular linear and quadratic Casimirs and momenta, can sometimes be conserved too, depending on the details of the equations under consideration and the form of discretization employed.
Moreover, it has a putative KIR motif and its interaction with both Keap1 and Atg8a appears to be conserved, too [ 73, 238, 239].
Requiring the entire CRM regions to be conserved is too restrictive, perhaps only those 6-14 bp long TFBSs within the CRMs are conserved.
The environment is more likely to be conserved by such practices, too.
It must be conserved.
It should be conserved and strengthened.
We discussed that charge must be conserved.
Because proteins which are placed in cohesive areas (i.e. modules) tend to be evolutionary conserved we wonder if their interactions are conserved too.
Since the binding sites are conserved too, as indicated by the sequence logos in figure 2b/c, the pipeline considered all regulations as transferable from CG to CE.
In order to determine, if such an arrangement is conserved in YqeH too, a combination of homology modeling and site-directed mutagenesis was employed.
I question the title which I think concludes one step too far: yes the CMG complex is conserved in all Archaea and Eukarya, but I think the evidence so far only allows the conclusion that this is likely to be a component of the DNA replication system.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com