For substances produced or imported in the 10 metric tonnage band, the data required in REACH will be enough to apply the classification criteria for skin and eye irritation and acute (mammalian) toxicity.
But as the American Trucking Association's latest data show the tonnage being shipped in June was down 13.6% year on year, an even bigger drop than that recorded in May.
Comments from ACACON highlighted two further attractions of in silico methods: "To supplement the information level for lower tonnage chemicals with limited test information requirements" "As a 'glue' between in vitro data in ITS approaches".
If even the different nanoforms of a substance were treated as different substances, such an approach would need very low tonnage triggers for the registration and data obligations in REACH.
We first summarize the data requirements for different tonnage bands, and then relate these requirements to the requirements of hazard assessment.
For the ≥ 1,000 metric tonnage band, additional (long-term) effect data on sediment living organisms, terrestrial organisms, and plants can be required, as well as additional data on bird reproduction and a carcinogenicity study (REACH annex X).
Employing European firm- and country-level data, the impact of the tonnage tax on organizational form choice is studied empirically.
The data requirements accumulate over the tonnage bands, such that for substances produced or imported in quantities of ≥ 10 metric tons/year, the data requirements for substances produced or imported in quantities of ≥ 1 metric tons/year are also applicable, and so on.
In what follows, we summarize the data requirements in each of these tonnage bands.
