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Endothelial-derived microparticles (EMPs) are a novel biological marker of endothelial injury and vascular tone disorders [11], [12].
The persistently elevated beta power observed here is indicative of elevated local inhibitory network activity, consistent with the muscle relaxant properties of diazepam, and its use in the treatment of centrally mediated muscular tone disorders [Elkassabany et al., 2006].
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Another study in a Chinese population supported the hypothesis that the abnormalities of VSMCs that alter the intrinsic contractile state of the cell can directly cause abnormal vascular tone and disorders of BP regulation [36].
The most common movement disorder in CP is spastic paresis, defined as a posture and movement dependent tone regulation disorder [ 3].
After months of testing, the various diagnoses began to roll in: blindness, undeveloped fine and gross motor skills, low muscle tone, autism, seizure disorders, speech delays.
The question now is the obvious one: will Trump's latest episode of narcissistic personality disorder, tone-deafness and unpatriotic, possibly criminal behavior finally do him in?
Besides, BDNF has complex interactions with sympathetic neurons[12], [13] and has been implicated in disorders of vascular tone dysregulation [14].
The involved extremity may demonstrate disorders in muscle tone, dyskinetic and atactic motor disorders as well as a reduction in strength and sensibility.
Spasticity is regarded as a disorder of muscle tone secondary to a hypersensitivity to the stretch reflex.
Dopaminergic replacement therapies in the form of the dopamine precursor l-DOPA as well as dopamine agonists and monoamine oxidase inhibitors aim at restoring striatal dopaminergic tone to alleviate the movement disorder.
83, 84 Carriers of deletions involving the gene CHRNA7 have severe mental disability, seizure disorders, and low muscle tone.
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