Your English writing platform
Discover LudwigExact(9)
As long as Toll activity is globally provided so that sog can also be activated in the dorsal half of the egg, a new round of patterning can be initiated dorsally.
DOI: http://dx.doi.org/10.7554/eLife.07187.016 Given that Toll activation is long known to cause melanization (Gerttula et al., 1988), we examined Toll activity in shi i adipocytes, but found that shibire knock-down did not cause Toll pathway activation, as evidenced by lack of Drs-GFP induction and absence of nuclear Dorsal localization (not shown).
They found that Toll activity in Drosophila larvae is negatively regulated by sumoylation controlled by the β-arrestin gene Kurtz.
This had been our proxy for Toll activity in Nasonia where we also lack anti-Dorsal antibodies.
Defective endocytosis or excess secretion induced by Toll activity cause PM overgrowth in fat body adipocytes, which leads to hyperconvoluted PM morphology and pericellular trapping of Collagen IV and other extracellular matrix (ECM) proteins in the cell cortex.
Furthermore, the atl mutant triggered a stronger induction of drosomycin expression (frequently used as a read-out for Toll activity) when normalized for the same number of infecting bacteria.
Similar(51)
In all, our analysis indicates that PM overgrowth and fibrotic deposits upon Toll activation result from increased secretory activity.
This experiment is also essential to understand how Atl influences Toll pathway activity (point 2b) 3) Results concerning the synergistic action of TagO and Atl should be moved to the Results section rather than briefly mentioned in the Discussion.
The US economy has shrunk at its fastest rate since the depths of the recession five years ago as it emerged that the harsh winter took a far bigger toll on activity than previously estimated.
Paul Dales, senior United States economist at Capital Economics, said uncertainty caused by the recession in Europe, the slowdown in Asia and impending tax increases and spending cuts in the United States "is taking its toll on activity".
This experiment is also essential to understand how Atl influences Toll pathway activity (point 2b).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com