Sentence examples for tolerant dose from inspiring English sources

Moreover, at the tolerant dose, this novel conjugate exhibited significantly better antitumor effect than that of Taxol formulation.

This research suggests that NLC/PI is a new potential candidate for Dac delivery to overcome the limitations of short half-life, and low tolerant dose of the drug.

These studies are consistent with in vitro mechanistic studies that tolerant dose L-LPS tempers the pro-inflammatory cytokine storm (Morris and Li, 2012).

However, previous studies solely examined the potential beneficial effects of "tolerant" dose L-LPS in animal models of sepsis (Kopanakis et al., 2013, Landoni et al., 2012).

Male Balb-C mice received LPS (1 mg/kg), a tolerant dose, and controls received 0.9% physiological serum during 5 days, both receiving on day 7 a LPS lethal dose (20 mg/kg).

As shown in Fig. 5A and consistent with previous studies, we observed that neutrophils cultured with 1 μg/mL tolerant dose L-LPS had significantly elevated levels of p-ERK.

Because the induction of apoptosis in inflammatory synoviocytes is the main goal for intra-articular gene transfer, a transient, localized, immune tolerant and dose dependent gene transfer may be achieved by direct intra-articular injection of apoptosis inducers carried by a suitable vector, controlled to infect only synovial cells but not chondrocytes in cartilage.

In order to improve the electron tomogram quality of dose tolerant specimens, we developed a multiple-tilt series data acquisition scheme for the EMT.

In rabbit aorta made tolerant by large doses of nitroglycerin, ALDH2 dehydrogenase activity was inhibited by ∼50%.

Oxygen-tolerant rats, which hae increased activities of pulmonary enzymes which combat lipid peroxidation, were also tolerant to lethal doses of paraquat as indicated by an increased paraquat LT50.

We aim to study how cells become tolerant to a toxic dose of this drug, and the relationship between caffeine and oxidative stress pathways.