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The linear decrease in salinity tolerance with an increase in inbreeding coefficient suggests that inbreeding depression for salinity tolerance results from additive combination among the loci responsible for inbreeding depression.
This improved drought tolerance results from up-regulation of stress-responsive genes RD29A, COR15A and DREB1A/ CBF3.
Multidrug tolerance results from drug-induced quiescence, which enables parasites to survive exposure to unrelated antimalarial drugs that inhibit a variety of metabolic pathways.
The homeostatic theory of drug tolerance [ 11] claims in a modern form that the functional tolerance results from altered function or expression of proteins in a way to reduce the effects of the drugs.
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No adverse effects on feeding tolerance resulted from this treatment.
FLA consisting of AMPS and DMAM (coded as ADM) showed the best water-retaining capacity and had a high temperature tolerance, resulting from strong rigidity of ADM molecule due to the existence of −CH3.
To further improve the performance of FLA, N,N-dimethyl acrylamide (DMAM) was used instead of AM to copolymerize with AMPS, and the copolymer synthesized (coded as ADM) was found to have a stronger temperature tolerance, resulting from reinforcement of molecular rigidity due to the existence of −CH3 (Guo et al. 2012).
It was initially considered that this lack of central tolerance resulted from the lack of expression of these genes in the thymus.
The latter finding is supported by our results, where tolerance resulting from OVA aerosol at 7 8 weeks of age persisted at least 8 weeks and was not overcome by in utero ETS exposure.
Of note, in Goto-Kakizaki rats (a nonobese rat model of T2DM) administration of exendin- 9 39) has bexendin- 9 39totally reverse thasimproved glucose tolerance resulting from duodeno-jejunal exclusion surgery (an experimental metabeenc shownry similar to RYGBP) (19).
Although multivariate analysis has little to say about detailed molecular mechanisms of hypoxia tolerance, the results from PCA extracted a list of metabolites that may play an important role in these tolerance mechanisms.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com