Sentence examples for tolerance development from inspiring English sources

During immunological tolerance development, effector TH2 cells enter a state of anergy and fail to develop specific T effector cells which mediate resistance.

"For years we've been studying simple responses such as intoxication and tolerance development," Dr. Heberlein said.

Tolerance development was assessed by tail-flick latency (TFL).

Prolonged MDPV treatment resulted in tolerance development after 1 week of drug withdrawal.

This concept of "host tolerance" aims at a tolerance development of the host on the pathogen.

injection of gabapentin (GBP) on the antinociceptive effect of morphine and tolerance development using a tail-flick latency test.

These results suggest that nitrate tolerance is associated with decreased endogenous formation of hydrogen peroxide, which attenuates nitrate tolerance development.

There are some reports regarding the inhibitory effect of pain on tolerance development to analgesic effect of opioids.

The 0.1 mg/kg/day NTG dose significantly attenuated tolerance development, while the other doses had no significant effect.

A drug free treatment milieu is therefore vital for securing the optimal effect of pharmacological treatment and minimizing the hazards of intoxications and cross-tolerance development.

Induction of GST activity under abiotic stress conditions has been considered an important factor in stress-tolerance development in plants (Dixon et al. 2010; Hasanuzzaman et al. 2012).