"tolerable toxicity" is correct and usable in written English.
You can use it to describe the amount of a chemical, substance, or agent that can be taken into the body without causing harm. For example, "The researchers were able to reduce the levels of the chemical to a tolerable toxicity."
Doses were based on previous experience and reflected maximum tolerated mouse doses that were associated with tumour response with tolerable toxicity (Ganapathi et al, 1988).
A high absorbed radiation dose is being delivered to tumours with a tolerable toxicity in normal non-targeted tissues.
The drug makers'rationalal' is that the complex drugs provide more tolerable toxicity for Doxil® compared with free doxorubicin!
A high absorbed dose is being delivered to tumours with a tolerable toxicity in normal non-targeted tissues [1 3].
This study demonstrates the possibility of treating small, solid colon carcinoma tumors with α-emitting radionuclides such as 211At bound to mAbs, with tolerable toxicity.
At any point in a trial, the dose given is that with estimated toxicity deemed closest to the maximum tolerable toxicity.
The phase II clinical trial demonstrated potent antitumor activity and tolerable toxicity profile by mogamulizumab monotherapy (Ishida et al., 2012), which led to approval by the regulatory authority in Japan in 2012.
Although substantial progress has recently been made in this area using parametric approaches, the method that is widely used is based on treating small cohorts of patients at escalating doses until the frequency of toxicities seen at a dose exceeds a predefined tolerable toxicity rate.
3-[3- 4-Cyano-1,5-diphenyl-1H-pyrazole-3-yl -1- 4-methylphenyl -1H-pyrazole-4-carbonyl]-1,5-diphenyl-1H-pyrazole-4-carbonitrile (27c) and 3-[3- 4-Cyano-1,5-diphenyl-1H-pyrazole-3-yl -1- 4-methylphenyl -1H-pyrazole-4-carbonyl]-1,5-diphenyl-1H-pyrazole-4-carbonitrilety in a nanomolar range against certain types of breast and ovarian tumors with tolerable toxicity.
Nab-paclitaxel can be combined with fluoropyrimidine with tolerable toxicity.
These have shown better response rates and tolerable toxicity levels.
