Sentence examples for tolerability threshold from inspiring English sources

Optimal schemes were defined as the ones which maximized DNA damage in cancer cells under the constraint of DNA damage in healthy cells not exceeding a tolerability threshold.

Exogenous agents that increase ROS generation or decrease antioxidant capacity will shift the redox balance and result in an overall increase in the level of ROS, which when above a cellular tolerability threshold may induce cell death [11].

The intensity of moxibustion is just below the individual tolerability threshold.

The 312 patients with positive intolerance tests after May 2010 were referred to an experienced dietician (CW) for a standardised 4-week dietary adaptation, consisting of a diet low in saccharides and polyols for 1 week and subsequent weekly introduction of defined classes and amounts of fructose-, fructan-, inulin- and lactose-containing food to determine individual tolerability thresholds.

The high frequency of switching between various ESAs is likely to be attributed to either ineffectiveness (missed achievement of a therapeutic goal, i.e. a predefined hemoglobin threshold), tolerability, or physician/patient preference due to differences in the frequency or route of administration between various ESAs, which may affect patient compliance [ 20].

Two give-a-shits strains the threshold of tolerability.

Thus, in some cases, DHA can make possible to overcome the maximum threshold of ROS tolerability by cancer cells, bypassing thus the oxidative stress resistance [ 49].

7 Second, the threshold criteria defining tolerability in the 10 patients were unrealistically higher than the conventional criteria used to define dose-limiting toxicity in phase I trials.

The investigators noted that the flexible Framingham score provides for use of different thresholds of risk, which is important when tolerability may vary according to the clinical situation.

Concerning tolerability and safety, MK-0974 was generally well-tolerated.

The secondary safety objectives included: comparison of severity of neuropathy AEs (defined as for the primary objective), patient-reported neurotoxicity questionnaire (PNQ), and vibration sensitivity (vibration perception threshold [VPT]); time to onset and resolution of neuropathy; and overall safety and tolerability.