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One example for such a process is the genetic toggle switch model that typically leads to multi-stable solutions [ 25].
With increasing axial loading cycles, the screws can begin to toggle, which decreases the friction force and leads to plate loosening.
Bit line toggling of SRAM systems in write operations leads to the largest portion of power dissipation.
When Rpd3L binds to the FLO11 promoter, Sfl1 is excluded from the PWR1 promoter, which leads to Flo8 associating with the toggle sites to activate PWR1 and concomitantly blocks ICR1 transcription.
An interesting aspect of FLO11 regulation is the toggle switch that results from competition between Sfl1p and Flo8p and leads to variegated FLO11 expression (Bumgarner et al. 2009, 2012).
Every lead leads to another lead.
It is in fact well-known that including self-activation in toggle switch systems can lead to tristability (Huang et al., 2007; Zhou & Huang, 2011; Lu et al., 2013).
The dynamics of the autoinducer (investigated in detail in [15]) introduces an additional feedback loop into the toggle switch and can lead to oscillatory behavior even in isolated cells [15].
