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In these neighborhoods, conditions were, as in areas hit today, problematic and dangerous.
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Then there were fewer than 5,000 problematic drug users in the UK.
He said the group had identified some 8,000 problematic sites in the last 12 months, a 30percentt spike over last year.
Many viewers resisted these plots, finding them off-putting or, as Tumblr might have phrased it had it existed in 2001, problematic.
Years of problematic reports, including issues ranging from documentation troubles to animals in extreme distress, led the U.S.D.A. to file an enforcement action, in 2012, accusing Santa Cruz Biotechnology of willful violation of the Animal Welfare Act; a hearing was recently set for July.
Kroll, a private investigation and cybersecurity firm, has trawled the social media accounts of potential signings for several Premier and Champions League clubs, checking their posts on Twitter, Facebook, Instagram and other platforms against a list of more than 1,000 problematic words.
Based on the CFA results and Anderson and Gerbing (1988), problematic indicators were deleted for the measurement model respecification.
Indeed, AZD9773 competes with various commercially available TNF-α detection Ab systems and novel phage-Ab anti-TNF binding antibody fragments (data not shown), making detection of TNF-α in the presence of AZD9773 problematic.
As noted in a previously published article (Calabrese 2005a), Problematic in the general area of research is that investigators who report findings on in vitro tumor cell proliferation do not typically cite responses in other systems such as the immune that could affect tumor responses, thereby rarely approaching an integrative assessment of the whole organism.
Hence, while seemingly obvious, upon closer examination the brain-centered view (endorsed by prominent scholars, such as Koch 2004; Chalmers 2000; Metzinger 2000; Crick and Koch 1990 , 1998 Crick 1996) appears problematic.
I like Buffett's portfolio for 2010, but 2009 is problematic.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com