Sentence examples for to warrant further development from inspiring English sources

Patients' initial interest appears high enough to warrant further development and testing.

A number of analogs were effective at reducing cholesterol in acute and chronic in vivo models but they lacked sufficient chronic in vivo activity to warrant further development.

In summary, some SOFA-HDV ribozymes exhibited sufficiently high cleavage levels of the IRES that they significantly reduced the luciferase activity; however, the observed level of replicon inhibition was never high enough to warrant further development of the SOFA-HDV ribozyme as an antiviral drug against HCV.

If at least four responses were observed, then the activity of irinotecan as demonstrated in this study would have been sufficiently promising to warrant further development.

Unfortunately, the threefold selectivity between MRC-5 and T. brucei is suboptimal, but the selectivity is sufficient to warrant further development of the compound series.

dose was also determined to warrant further development as it was estimated to provide at least 10% additional efficacy over 5 mg b.i.d. at week 12 (Table 1 ).

The results presented in this study suggest these compounds warrant further development with a view to assessing their clinical activity.

Ideally, in vitro high-throughput toxicity screens can be used to rank and prioritize drug candidates, environmental contaminants, and commercial chemicals, which warrant further development or testing.

Clearly, HNK may warrant further development, either as a single drug or as a means to increase efficacy in combination with other antitumour drugs, but this will depend on tumour type.

These observations suggest that specific PAA toxin combinations warrant further development as novel therapeutics.

Thus, this study might provide a new class of lead structures that warrant further development as potential anti-resorptive agents.