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This virtual patient helps to test a large panel of clinical situations to validate the rules implemented and to detect any bugs.
The data from patients with at least two such recorded values were used to validate the rules outlined above, applied recursively from the first value.
ML helped to validate the rules.
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For instance, the following calculation demonstrates the Rule D(4) validation in our SFSD, whereas it is more obvious to validate the rule D(1) to D 3).
Subsequently, we assessed a different prospective cohort of consecutive patients to validate the rule.
Two hundred and fifty six eligible children were invited to take part in the cohort study to validate the prediction rule.
18 This is the first study to validate the Wells rule in a primary care setting, in a large population of almost 600 patients with suspected pulmonary embolism.
Independent data from 158 patients with CDI obtained from a UK teaching hospital, as described by the Bhangu et al. (2010) study [ 11] was used to validate the prediction rule generated in the derivation cohort.
Therefore, to validate the decision rule in a new population, this data will be collected simultaneously in the third hospital, the non-teaching hospital, using the same approach as in the other two hospitals.
20 33 34 35 36 37 38 However, owing to complete missing information on the predictors oxygen saturation and body temperature in our dataset, we were not able to validate the revised Pisa rule, the PERC rule, and the Charlotte rule, leaving five models for further evaluation.
Unfortunately, XSD is not sufficient to validate the many semantic rules defined in the SBGN specification.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com