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On the basis of the current available results from the literature, it is desirable to perform further multicenter trials in order to validate definitively these biomarkers, taking into account the importance to early assess the capacity of repair of the renal tubular cells.
Experimental data regarding mitotic recombination rates or the variations of dCTPs and dGTPs during S phase are required to validate definitively one of the two models, but in any case, the fit of the models to the data suggests that C. albicans and C. dubliniensis constitute so far unique examples of GC content evolution driven either by mitotic recombination or replicative errors.
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Further investigation is needed to validate these findings more definitively and to show whether monitoring PCT will improve patient outcomes and health care resource use.
The utility of this approach to patient management, based on the findings described in this study, would be validated definitively if interventions that enhance specific QoL parameters are shown to enhance survival.
Thus, IL-10 has not been established definitively in SIDS pathogenesis, with failure to validate and replicate initial signals derived from small sample sized cohorts.
The involvement of Neu1 is validated definitively using bone marrow cells from Neu1-deficient mice.
If governments need leaks to validate their secrecy, leakers need secrecy to validate their leaks.
There's little evidence to validate this.
ARG was performed to validate PET results.
You need to validate before you execute.
You need to validate your assumptions.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com