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The 5-AZA-CdR was selected as a representative demethylation agent to validate the principle of the TDQ method on three levels: significant dose response relationships between the concentration of 5-AZA-CdR and the methylation level of promoters, mRNA expression level of the EGFP gene, and the fluorescence intensity of EGFP proteins.
So, if the Simpson case were a meaningful precedent, it would be important to validate the principle that the criminal-justice system operates one case at a time; acquittal in one trial shouldn't prejudice a defendant's fate in another.
The 5-aza-2'-deoxycytidine (5-AZA-CdR) was selected as a representative positive demethylation agent to validate the principle of the TDQ method (Fig. 1) on three levels: dose response relationship exploration between the concentration of 5-AZA-CdR and the methylation level of CMV promoters, mRNA expression level of EGFP gene, and the intensity of cellular fluorescence intensity (Table 1).
A pseudorandom 500 Mbps QPSK signal is used to validate the principle of operation.
Experimental investigation has been carried out to validate the principle.
Research was performed to validate operation principle and to investigate dynamic characteristics of the motor.
The finite element analysis (FEA) is utilized to validate the principle of the ARDMRD and obtain the magnetic properties of its magnetic circuit.
Numerical investigation of the piezoelectric motor based on finite elements method was performed in order to obtain natural frequency and modal shape of the stator, to investigate dynamic characteristics and to validate operation principle of the motor.
The strong interest in targeting the p53 MDM2 interaction has led to the identification of several macromolecular tools that helped to validate the principle of this p53-activating approach.
To validate the principle underpinning the database and provide another example of the usefulness of dbWFA, we analysed the functional annotation of the transcripts specifically expressed during either the ECD or SPA phase of grain development.
Two numerical examples are presented to validate the main principle and the implementability of the scheme.
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