Sentence examples for to undergo class from inspiring English sources
The results demonstrated that human B cells developed by DRAG were functional as they secreted all human immunoglobulin classes, whereas those from control mice were impaired in their ability to undergo class switching and secreted only IgM.
It is known that in mice, Th1 biased T helper cell responses favor the production of antigen specific IgG2a and IgG3 while Th2 responses prompt B cells to undergo class switch recombination towards IgG1 and IgE [24], [25], [27].
B1 B cells have also been found to undergo class switch recombination from IgM to IgA.
She said the parents were ordered to undergo classes in child care.
Since the latter cells are enriched in the peripheral blood, it is now possible to perform functional assays and determine whether CD38- B cells are similar to mouse B cells that lack RelB and that are defective in proliferative responses but are able to secrete immunoglobulins and undergo class switching [ 23].
TLR9-deficient autoreactive B cells no longer undergo class switching to pathogenic immunoglobulin isotypes (IgG2a and IgG2b), these TLR9−/− mice having significantly smaller IgG deposits in the glomeruli and a prolonged survival compared with their TLR9 sufficient littermates.
Naïve B cells undergo class switching leading to the development of memory B cells and plasma cells that produce IgE.
T follicular helper (TFH) cells have been shown to be critically required for the germinal center (GC) reaction where B cells undergo class switch recombination and clonal selection to generate high affinity neutralizing antibodies.
To produce a functionally diverse antibody repertoire B lymphocytes undergo class switch recombination.
Within the germinal center (GC), antigen activated B cells undergo class switch recombination (CSR) and somatic hypermutation (SHM).
The GC is the site where antigen activated naïve B cells migrate, proliferate and undergo class switch recombination, antibody gene diversification and affinity maturation [10].
